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Background Reports of methotrexate for chronic urticaria are anecdotal.
Objectives To assess the effectiveness of methotrexate in steroid‐dependent chronic urticaria, its impact on steroid reduction and any differences in response between patients with and without functional autoantibodies.
Methods A retrospective case‐note review of 16 patients with steroid‐dependent chronic urticaria treated...
The low number of peripheral blood basophils in chronic urticaria patients detected by metachromatic granule stains may be due to loss of stainable granules or reduced cell numbers. We have developed a new flow cytometric method for counting basophils by double staining membrane markers with anti-IgE and a noninhibitory monoclonal antibody (29C6) which binds the a-subunit of high affinity IgE receptors...
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