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Rumination is closely linked to the onset and maintenance of major depressive disorder (MDD). Prior neuroimaging studies have identified the association between self‐reported rumination trait and the functional coupling among a network of brain regions using resting‐state functional magnetic resonance imaging (MRI). However, little is known about the underlying neural circuitry mechanism during active...
Objective
Major depressive disorder (MDD) and bipolar disorder (BD) are considered whole‐brain disorders with some common clinical and neurobiological features. It is important to investigate neural mechanisms to distinguish between the two disorders. However, few studies have explored the functional dysconnectivity between the two disorders from the whole brain level.
Methods
In this study, 117...
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