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Lidocaine has been reported to induce apoptosis on rabbit corneal endothelial cells. However, the apoptotic effect and exact mechanism involved in cytotoxicity of lidocaine are not well‐established in human corneal endothelial (HCE) cells. In this study, we investigated the apoptosis‐inducing effect of lidocaine on HCE cells in vitro. After HCE cells were treated with lidocaine at concentrations of...