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ObjectiveTo determine whether activation of transient receptor potential vanilloid 4 (TRPV‐4) induces inflammation in the rat temporomandibular joint (TMJ), and to assess the effects of TRPV‐4 agonists and proinflammatory mediators, such as a protease‐activated receptor 2 (PAR‐2) agonist, on TRPV‐4 responses.
MethodsFour hours after intraarticular injection of carrageenan into the rat joints, expression...