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BackgroundMicroRNA‐122 (miR‐122) is an important host factor for hepatitis C virus replication. Administration of miravirsen, an anti‐miR‐122 oligonucleotide, resulted in a dose dependent and prolonged decrease in HCV RNA levels in chronic hepatitis C patients.
AimTo assess the plasma level of various miRNAs in patients dosed with miravirsen.
MethodsWe included 16 of 36 chronic hepatitis C patients...