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The main objective of this research has been to study the efficiency of chitosan as an ocular drug delivery vehicle for topically applied vancomycin in rabbit eyes. Vancomycin 50 mg/mL was reconstituted in four preparations, namely: in Tears Naturale II™, in 0.9% w/v aqueous sodium chloride, and in 0.1% and 0.3% w/v chitosan solutions in 1% aqueous L(+)‐lactic acid. Twenty‐five microliters of vancomycin...