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Aim
The aim was to evaluate the beneficial effect of early mitogen‐activated protein kinase (MEK)1/2 inhibition administered at a clinical relevant time‐point using the transient middle cerebral artery occlusion model and a dedicated rodent magnetic resonance imaging system (9.4T) to monitor cerebrovascular changes non‐invasively for 2 weeks.
Method
Transient middle cerebral artery occlusion was...