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Background
Eosinophilic chronic rhinosinusitis (ECRS) is a chronic inflammatory disease, characterized by eosinophilic infiltration, T‐helper type 2 (Th2‐type) response, and olfactory dysfunction. A master regulator of Th2‐type inflammation, thymic stromal lymphopoietin (TSLP), is important for basophil activation. TSLP‐elicited basophils are a key factor in the pathogenesis of ECRS.
Methods
In...