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Background
Pru p 3 and Pru p 7 have been implicated as risk factors for severe peach allergy. This study aimed to establish sensitization patterns to five peach components across Europe and in Japan, to explore their relation to pollen and foods and to predict symptom severity.
Methods
In twelve European (EuroPrevall project) and one Japanese outpatient clinic, a standardized clinical evaluation...
Background
Around 20 years ago, a 60‐ to 70‐kDa protein was reported as a major allergen of mugwort (Artemisia vulgaris) pollen. This study was to identify and characterize its molecular properties.
Methods
Sera from 113 Chinese and 20 Dutch Artemisia‐allergic/sensitized subjects (and pools thereof) were used to identify the 60‐ to 70‐kDa allergen. Pollen extracts of seven Artemisia species were...
Background
Component‐resolved diagnosis (CRD) has revealed significant associations between IgE against individual allergens and severity of hazelnut allergy. Less attention has been given to combining them with clinical factors in predicting severity.
Aim
To analyze associations between severity and sensitization patterns, patient characteristics and clinical history, and to develop models to...
Background
Most studies on the relationship between helminth infections and atopic disorders have been conducted in (sub)tropical developing countries where exposure to multiple parasites and lifestyle can confound the relationship. We aimed to study the relationship between infection with the fish‐borne helminth Opishorchis felineus and specific IgE, skin prick testing, and atopic symptoms in Western...
Background
Data are lacking regarding the prevalence of food sensitization and probable food allergy among general population in India. We report the prevalence of sensitization and probable food allergy to 24 common foods among adults from general population in Karnataka, South India.
Methodology
The study was conducted in two stages: a screening study and a case–control study. A total of 11 791...
Background
The safety and tolerability of a mite allergoid subcutaneous allergen immunotherapy (SCIT) product was previously established. The aim of this study (EudraCT number: 2011–000393–61) was to find the optimally safe and effective allergoid dose by evaluating several dosages in patients with house dust mite (HDM)‐induced allergic rhinoconjunctivitis (ARC) using a titrated nasal provocation...
BackgroundHazelnut and peanut are botanically unrelated foods, but patients are often sensitized and allergic to both, for reasons that are not well understood.
MethodsTo investigate molecular cosensitization and cross‐reactivity to peanut in hazelnut‐sensitized individuals, children (n = 81) and adults (n = 80) were retrospectively selected based on sensitization to hazelnut. IgE to hazelnut extract,...
BackgroundComplaints of ‘food allergy’ are increasing. Standardized surveys of IgE sensitization to foods are still uncommon and multicountry surveys are rare. We have assessed IgE sensitization to food‐associated allergens in different regions of Europe using a common protocol.
MethodsParticipants from general populations aged 20–54 years in eight European centres (Zurich, Madrid, Utrecht, Lodz,...
EoE patients show variable sensitization patterns to food and aeroallergens. The value of allergy testing in adult EoE patients is unclear. Component‐resolved diagnosis (CRD) may offer additional insights into sensitization patterns. The aim of this study was to characterize sensitization patterns in adult EoE patients using CRD. Serum from 76 patients (17 female), age 38.6 ± 1.5 years, was analyzed...
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