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CD4+ Tregs specific for noninherited maternal antigens (NIMAd) are detectable in some but not all B6 × BDF1 backcross, H‐2b homozygous offspring, and their presence is strongly correlated with extent of maternal (BDF1) microchimerism. We hypothesized that the level of pretransplant donor antigen‐specific Tregs could predict allograft tolerance. To test this idea, mice were screened for bystander suppression...