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Aim
To describe systemic nicotine exposure and subjective effects of electronic cigarettes (e‐cigarettes) in people who use both e‐cigarettes and cigarettes (dual users), including within‐subject comparisons of e‐cigarette and cigarette use.
Design
Two‐arm, counterbalanced cross‐over study. Participants used their usual brand of e‐cigarette or cigarette during a standardized session in a 2‐week...
To describe the effect of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes.11 males and 3 females participated in a 3-day inpatient crossover study with strawberry, tobacco, and their usual flavor e-liquid. Nicotine levels were nominally 18mg/mL in the strawberry (pH 8.29) and tobacco (pH 9.10) e-liquids and ranged between 3–18mg/mL in the usual brands (mean pH 6.80). Each day...
Aims
To measure the systemic retention of nicotine, propylene glycol (PG) and vegetable glycerin (VG) in electronic cigarette (e‐cigarette) users, and assess the abuse liability of e‐cigarettes by characterizing nicotine pharmacokinetics.
Design
E‐cigarette users recruited over the internet participated in a 1‐day research ward study. Subjects took 15 puffs from their usual brand of e‐cigarette...
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