The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Oxycodone is a highly prescribed opioid and its abuse has been rampant. Accumulating evidence shows that the cannabinoid CB1 receptor (CB1R) plays a key role in mediating rewarding effects to opioids. However, the downstream signalling of CB1R induced by oxycodone remains unclear. The neuropeptide oxytocin is well known as a potential remedy for drug addiction. Thus, our study aims to explore the...
Oxycodone is one of the most commonly used analgesics in the clinic. However, long‐term use can contribute to drug dependence. Accumulating evidence of changes in DNA methylation after opioid relapse has provided insight into mechanisms underlying drug‐associated memory. The neuropeptide oxytocin is reported to be a potential treatment for addiction. The present study sought to identify changes in...
ObjectiveThis study explored the association between the risk of carbamazepine (CBZ)–induced Stevens‐Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and CBZ dose, dose‐adjusted concentration, and ABCB1,CYP3A4,EPHX1,FAS,SCN1A,MICA,andBAG6 polymorphisms in patients of Han ethnicity with epilepsy who were living in northeastern China.
Materials and methodsWe determined the genotypes of...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.