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Background Inguinal hernia repair is one of the most common surgical operations globally; more than 20 million groin herniae are repaired annually worldwide. Recurrence after an inguinal hernia operation is a considerable clinical problem. Another remaining problem after hernia surgery is the occurrence of chronic pain. Up to now, the use of synthetic meshes is the standard procedure, but there is...
Mit zielgerichteter Tumortherapie konnte in den letzten Jahren die Lebensqualität vieler Krebspatienten verbessert und sogar ihr Überleben verlängert werden. Möglich wurde dies durch das wachsende Verständnis tumorspezifischer Signalwege. Auch beim Urothelkarzinom wurden spezifische Veränderungen von Tumorsignalwegen identifiziert. Dazu gehören Mutationen von FGFR3, HRAS und PIK3CA, die insbesondere...
A variety of high-resolution atmospheric-model applications are running on the high performance computer cluster at Dugway Proving Ground (DPG), with the objective of providing accurate weather information to forecasters, test managers and planners, and decision-support staff at ATEC test ranges. The foundation of these applications is the 4D Weather (4DWX) forecasting system, which is built upon...
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