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—Using Raman spectroscopy, atomic force microscopy, and laser interferometry we found that variations in insulin-like growth factor (IGF-1) and purinergic compounds such as ATP in the blood influence the hemoglobin distribution and hematoporhyrin conformation in hemoglobin in erythrocytes. Our results suggest that receptor activation promotes changes in conformation of cytoskeletal protein molecules...
The influence of murine intestinal adenocarcinoma on the antioxidant status and hemoglobin content in the blood was analyzed. Murine adenocarcinoma was accompanied with a decrease of the nonprotein thiol concentration and an increase in ceruloplasmin. A conformational change in the globin molecule but not in the heme group was revealed in the hemoglobin molecule. The changes in the protein appear...
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