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Summary Background Despite considerable efforts there is no consensus regarding the ideal reconstruction method for the pancreatic remnant after pancreaticoduodenectomy (PD). Methods Overall, 86 patients who underwent PD for ductal adenocarcinoma were selected for analysis. One surgeon (RF) took responsibility of all pancreatic resections, either by operating personally or proctoring the procedure...
Sotrastaurin, a novel immunosuppressant, blocks early T cell activation through protein kinase C inhibition. Efficacy and safety of sotrastaurin with tacrolimus were assessed in a dose‐ranging non‐inferiority study in renal transplant recipients. A total of 298 patients were randomized 1:1:1:1 to receive sotrastaurin 100 (n = 77; discontinued in December 2011) or 200 mg (n = 73) b.i.d. plus standard...
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