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Introduction Ependymoma metastasis occurs usually along with local recurrence within 7 years after the initial diagnosis. Later spinal metastasis without local recurrence after the surgical resection has been rarely reported in patients with low-grade ependymomas but not with high-grade ependymomas. Here, we present a case with autopsy revealing late extensive supratentorial metastasis of a fourth...
BackgroundMegestrol acetate (MA) is an appetite stimulant with efficacy in promoting weight gain in adults with cancer‐associated anorexia–cachexia. Studies documenting MA efficacy in children, however, are limited. We present the first randomized, double‐blind, placebo‐controlled clinical trial of MA versus placebo in children with cancer and weight loss.
MethodsSubjects <18 years of age with...
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