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Inflammation is an underlying basis for the molecular alterations that link aging and age-related pathological processes. In a previous study, we found that secretory phospholipase A2 (sPLA2) induced cellular senescence in human dermal fibroblasts (HDFs). To further investigate the association of inflammation with cellular senescence, the effects of PGE2 on cellular senescence in HDFs were investigated,...
To identify plant extracts capable of inhibiting cellular senescence, the effects of plant extracts on adriamycin-induced cellular senescence in human fibroblasts, human umbilical vein endothelial cells (HUVECs), and vascular smooth muscle cells were investigated. After adriamcyin treatment, the effects of plant extracts on cellular senescence were evaluated by measuring senescenceassociated β-galactosidase...
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