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Network Function Virtualization is a recent and significant development applied in cloud datacenters, which can help service providers manage network services more flexibly and economically than using middle-boxes. User requests may demand different numbers of services in a chain, where the related flows can be directed to different physical machines (PMs) hosting required virtual network functions...
Background The tristetraprolin (TTP) family of mRNA-binding proteins contains three major members, Ttp, Zfp36l1, and Zfp36l2. Ttp down-regulates the stability of AU-rich element–containing mRNAs and functions as an anti-inflammation regulator. Methods To examine whether other TTP family proteins also play roles in the inflammatory response, their expression profiles and the possible mRNA targets...
Lipopolysaccharide (LPS) treatment causes the marked changes of gene expression in macrophages. Tristetraprolin (TTP), which is an mRNA-destabilizing protein that negatively regulates the expression of pro-inflammatory mediators, is induced by LPS. To delineate the molecular mechanism of LPS-stimulated TTP expression, several inhibitors blocking different signaling pathways were used initially. We...
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