Junko Ishijima

article

Specialized ribosomes control Hox mRNA translation and vertebrate tissue patterning

Nadya Kondrashov, Aya Pusic, Craig Stumpf, Kunihiko Shimizu, more

Developmental Biology > 2011 > 356 > 1 > 102

article

Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning

Nadya Kondrashov, Aya Pusic, Craig R. Stumpf, Kunihiko Shimizu, more

Cell > 2011 > 145 > 3 > 383-397

Historically, the ribosome has been viewed as a complex ribozyme with constitutive rather than regulatory capacity in mRNA translation. Here we identify mutations of the Ribosomal Protein L38 (Rpl38) gene in mice exhibiting surprising tissue-specific patterning defects, including pronounced homeotic transformations of the axial skeleton. In Rpl38 mutant embryos, global protein synthesis is unchanged;...

article

The ZW sex chromosomes of Gekko hokouensis (Gekkonidae, Squamata) represent highly conserved homology with those of avian species

Aya Kawai, Junko Ishijima, Chizuko Nishida, Ayumi Kosaka, more

Chromosoma > 2009 > 118 > 1 > 43-51

Populations of the gecko lizard Gekko hokouensis (Gekkonidae, Squamata) on Okinawajima Island and a few other islands of the Ryukyu Archipelago, Japan, have the morphologically differentiated sex chromosomes, the acrocentric Z chromosome and the subtelocentric W chromosome, although the continental representative of this species reportedly shows no sex chromosome heteromorphism. To investigate the...

article

Characterization of chromosome structures of Falconinae (Falconidae, Falconiformes, Aves) by chromosome painting and delineation of chromosome rearrangements during their differentiation

Chizuko Nishida, Junko Ishijima, Ayumi Kosaka, Hideyuki Tanabe, more

Chromosome Research > 2008 > 16 > 1 > 171-181

Karyotypes of most bird species are characterized by around 2n = 80 chromosomes, comprising 7–10 pairs of large- and medium-sized macrochromosomes including sex chromosomes and numerous morphologically indistinguishable microchromosomes. The Falconinae of the Falconiformes has a different karyotype from the typical avian karyotype in low chromosome numbers, little size difference between macrochromosomes...

article

The molecular basis of chromosome orthologies and sex chromosomal differentiation in palaeognathous birds

Chizuko Nishida-Umehara, Yayoi Tsuda, Junko Ishijima, Junko Ando, more

Chromosome Research > 2007 > 15 > 6 > 721-734

Palaeognathous birds (Struthioniformes and Tinamiformes) have morphologically conserved karyotypes and less differentiated ZW sex chromosomes. To delineate interspecific chromosome orthologies in palaeognathous birds we conducted comparative chromosome painting with chicken (Gallus gallus, GGA) chromosome 1–9 and Z chromosome paints (GGA1–9 and GGAZ) for emu, double-wattled cassowary, ostrich, greater...

article

Comparison of the Z and W sex chromosomal architectures in elegant crested tinamou (Eudromia elegans) and ostrich (Struthio camelus) and the process of sex chromosome differentiation in palaeognathous birds

Yayoi Tsuda, Chizuko Nishida-Umehara, Junko Ishijima, Kazuhiko Yamada, more

Chromosoma > 2007 > 116 > 2 > 159-173

To clarify the process of avian sex chromosome differentiation in palaeognathous birds, we performed molecular and cytogenetic characterization of W chromosome-specific repetitive DNA sequences for elegant crested tinamou (Eudromia elegans, Tinamiformes) and constructed comparative cytogenetic maps of the Z and W chromosomes with nine chicken Z-linked gene homologues for E. elegans and ostrich (Struthio camelus...

article

Two variable lymphocyte receptor genes of the inshore hagfish are located far apart on the same chromosome

Jun Kasamatsu, Takashi Suzuki, Junko Ishijima, Yoichi Matsuda, more

Immunogenetics > 2007 > 59 > 4 > 329-331

Variable lymphocyte receptors (VLR) generate enormous diversity through assembling highly diverse leucine-rich repeat (LRR) modules and presumably function as antigen receptors in jawless vertebrates. The hagfish, which constitute major extant members of jawless vertebrates along with lampreys, have two VLR genes designated VLRA and VLRB, whereas only a single VLR gene has been identified in the lamprey...

article

cDNA-based gene mapping and GC₃ profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids

Shigehiro Kuraku, Junko Ishijima, Chizuko Nishida-Umehara, Kiyokazu Agata, more

Chromosome Research > 2006 > 14 > 2 > 187-202

Mammalian and avian genomes comprise several classes of chromosomal segments that vary dramatically in GC-content. Especially in chicken, microchromosomes exhibit a higher GC-content and a higher gene density than macrochromosomes. To understand the evolutionary history of the intra-genome GC heterogeneity in amniotes, it is necessary to examine the equivalence of this GC heterogeneity at the nucleotide...

article

A novel family of repetitive DNA sequences amplified site-specifically on the W chromosomes in Neognathous birds

Kazuhiko Yamada, Chizuko Nishida-Umehara, Junko Ishijima, Takahiro Murakami, more

Chromosome Research > 2006 > 14 > 6 > 613-627

A novel family of repetitive DNA sequences was molecularly cloned from ApaI-digested genomic DNA of two Galliformes species, Japanese quail (Coturnix japonica) and guinea fowl (Numida meleagris), and characterized by chromosome in-situ hybridization and filter hybridization. Both the repeated sequence elements produced intensely painted signals on the W chromosomes, whereas they weakly hybridized...

article

Highly conserved linkage homology between birds and turtles: Bird and turtle chromosomes are precise counterparts of each other

Yoichi Matsuda, Chizuko Nishida-Umehara, Hiroshi Tarui, Asato Kuroiwa, more

Chromosome Research > 2005 > 13 > 6 > 601-615

The karyotypes of birds, turtles and snakes are characterized by two distinct chromosomal components, macrochromosomes and microchromosomes. This close karyological relationship between birds and reptiles has long been a topic of speculation among cytogeneticists and evolutionary biologists; however, there is scarcely any evidence for orthology at the molecular level. To define the conserved chromosome...

article

Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program

Hiroshi Masuya, Yuji Nakai, Hiromi Motegi, Norio Niinaya, more

Mammalian Genome > 2004 > 15 > 5 > 404-411

A mouse ENU-mutagenesis program at RIKEN GSC has been initiated to conduct a large-scale, genome-wide, early- and late-onset phenotypic screen of mutant mice. We screened about a hundred mice every week with a comprehensive set of phenotype assays including behavioral tests based on a modified SHIRPA protocol, blood tests (both clinical biochemical testing and hemogram), and measurement of locomotor...

article

A Spontaneous Mouse Mutation, mesenchymal dysplasia (mes), Is Caused by a Deletion of the Most C-Terminal Cytoplasmic Domain of patched (ptc)

Shigeru Makino, Hiroshi Masuya, Junko Ishijima, Yukari Yada, more

Developmental Biology > 2001 > 239 > 1 > 95-106

A recessive mouse mutation, mesenchymal dysplasia (mes), which arose spontaneously on Chromosome 13, causes excess skin, increased body weight, and mild preaxial polydactyly. Fine gene mapping in this study indicated that mes is tightly linked to patched (ptc) that encodes a transmembrane receptor protein for Shh. Molecular characterization of the ptc gene of the mes mutant and an allelism test using...

article

Dominant Lethality of the Mouse Skeletal Mutation Tail-short (Ts) Is Determined by theTsAllele from Mating Partners

Junko Ishijima, Hiroshi Yasui, Masae Morishima, Toshihiko Shiroishi

Genomics > 1998 > 49 > 3 > 341-350

Mice with the Tail-short (Ts) mutation have a short, kinky tail and numerous skeletal abnormalities, including a homeotic anteroposterior patterning problem involving the axial skeleton. The viability ofTsheterozygotes varies dramatically, depending on the mouse strain crossed with the mutant strain. At the extremes, the heterozygotes are viable or lethal prenatally. In this study, we found that laboratory...

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Search results for: Junko Ishijima

Specialized ribosomes control Hox mRNA translation and vertebrate tissue patterning

Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning

The ZW sex chromosomes of Gekko hokouensis (Gekkonidae, Squamata) represent highly conserved homology with those of avian species

Characterization of chromosome structures of Falconinae (Falconidae, Falconiformes, Aves) by chromosome painting and delineation of chromosome rearrangements during their differentiation

The molecular basis of chromosome orthologies and sex chromosomal differentiation in palaeognathous birds

Comparison of the Z and W sex chromosomal architectures in elegant crested tinamou (Eudromia elegans) and ostrich (Struthio camelus) and the process of sex chromosome differentiation in palaeognathous birds

Two variable lymphocyte receptor genes of the inshore hagfish are located far apart on the same chromosome

cDNA-based gene mapping and GC₃ profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids

A novel family of repetitive DNA sequences amplified site-specifically on the W chromosomes in Neognathous birds

Highly conserved linkage homology between birds and turtles: Bird and turtle chromosomes are precise counterparts of each other

Development and implementation of a database system to manage a large-scale mouse ENU-mutagenesis program

A Spontaneous Mouse Mutation, mesenchymal dysplasia (mes), Is Caused by a Deletion of the Most C-Terminal Cytoplasmic Domain of patched (ptc)

Dominant Lethality of the Mouse Skeletal Mutation Tail-short (Ts) Is Determined by theTsAllele from Mating Partners

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