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The remarkable molecular diversity of breast cancers affects therapeutic options and clinical outcome for patients. Understanding the cell of origin and the factors that impact stem cell differentiation and proliferation are crucial aspects for the development of effective breast cancer prevention, diagnostic, and therapeutic strategies. Evidence suggests that molecular subtypes, such as luminal and...
Inappropriate Met receptor tyrosine kinase signaling can produce proliferative, invasive, angiogenic, and antiapoptotic activities that contribute to malignant growth. Met can be activated by paracrine or autocrine mechanisms in a ligand-dependent fashion, or be constitutively activated by mutation and by other ligand-independent mechanisms. Because Met is inappropriately expressed in almost all types...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.