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Objective:. HMG CoA reductase inhibitors (statins) may exert a wide array of cholesterolindependent effects including antihypertrophic effects on the heart. Their role in the treatment of heart failure has not been studied. Methods and results:. 15 patients with heart failure NYHA II-III based on non-ischemic dilated cardiomyopathy were randomized in a double-blind study to 0.4 mg cerivastatin or...