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Metastasis to bone is a major complication of advanced cancer and occurs in more than 400,000 cancer patients each year. Bone metastasis can arise from many different tumor types, including breast, prostate, lung, renal cell, thyroid, and bladder cancer, and in patients with melanoma and myeloma. The development of bone metastasis in cancer patients contributes significantly to the morbidity and mortality...
A method of using IL-4, the use of IL-4 for the manufacture of a medicament and pharmaceutical compositions containing IL-4, for treating solid tumor growth by systemically injecting IL-4, such as hIL-4 or recombinant E. coli-derived IL-4, into mammals afflicted with solid tumors is disclosed.
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