The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The small-for-size syndrome reflects portal hyperperfusion in reduced-size livers such as cadaveric split livers or living-related donor grafts, presenting as a condition which might seriously impair postoperative liver regeneration. Using an experimental rat model, we investigated splenectomy as a measure to reduce portal hyperperfusion and its impact on postoperative recovery following extended...
Ischemic preconditioning (IPC) has been proven an effective strategy against hepatic ischemia-reper-fusion injury in both animal and human studies. However decreased protective effect was found in patients undergoing extended liver resection. The drastic reduction of the microvascular bed upon major hepatectomy is associated with exposure of remnant liver tissue to excessive portal perfusion. Herein,...
if temporary inflow occlusion is required during liver resection, the postoperative course might be complicated by ischemia-reperfusion (IR) injury. Steroids have shown to protect against hepatic IR injury, however, due to its anti-proliferative character concerns exist on its use on liver regeneration after resection. Using an experimental model, we investigated the effects of methylprednis-olone...