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Irradiation of blood derivatives is employed in blood banks to avoid transfusion-associated graft-vs-host disease. As irradiation can damage membranes and membrane proteins by generation of reactive oxygen species, we investigated whether the membrane permeability, Na+,K+–ATPase, and Ca2+–ATPase from red blood cell plasma membranes were altered by γ-irradiation. Whole blood was collected from healthy...