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In this work, we propose a plane-dependent maximum likelihood (ML) scatter scale estimation from the emission measurements. The scatter scales obtained are validated using a Monte Carlo simulation of a NEMA-like phantom, and results are shown from two whole-body patient scans.
Data acquisition in positron emission tomography (PET) with continuous bed motion (CBM) is more natural and flexible for whole body patient scan than conventional step and shoot mode. In this paper, we proposed a reconstruction method for CBM data that is able to accurately compensate gating effects on image quantification and uniformity by including gating signals into calculation of normalization...
Single bed motion correction algorithms are increasingly being used to model and compensate for the respiratory motion in clinical PET images. In this work we develop a multi-bed elastic motion correction algorithm and workflow for the MR-PET (Siemens biograph mMR) scanner. For validation of the proposed multi-bed motion algorithm we performed multi-bed NCAT phantom simulations as well as physical...
In positron emission tomography a scatter estimate is calculated prior to image reconstruction and is then added at each MLEM iteration to the estimated true counts to yield the estimated prompts. The absolute scale of the scatter is usually estimated by matching the scatter estimate to the data for those lines of response that do not intersect the patient. The goal of this work is to explore alternatives...
Time alignment of a positron emission tomography scanner (PET) is an important calibration as the nature of the data collected in PET is inherently time-correlated. This calibration is a key concern in scanners which employ time-of-flight (TOF) capability to localize events along a particular segment of a line of response. Emission data collected with TOF information requires the time difference measured...
LSO scintillators (Lu2Sio5:Ce) have a background radiation which originates from the isotope Lu-176 that is present in natural occurring lutetium. The decay that occurs in this isotope is a beta decay that is in coincidence with cascade gamma emissions with energies of 307, 202 and 88 keV. The coincidental nature of the beta decay with the gamma emissions allow for separation of the emission data...
The redundancy in 3D time-of-flight (TOF) PET data can be exploited to reduce data storage or to estimate unmeasured data samples caused by defective or missing detectors. Mathematically, redundancy is expressed by consistency conditions which can be expressed either in terms of the 3D Fourier transform of the data or as a pair of partial differential equations (PDE). The benefit of the latter is...
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