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This paper describes the development of a smartphone-based electrochemical biosensor module. The module contains a low power potentiostat that interfaces and harvests power from a smartphone through the phone's audio jack. A prototype with two different potentiostat designs was constructed and used to conduct proof of concept cyclic voltammetry experiments with potassium ferro-/ferricyanide (K4[Fe(CN)...
Over the past two decades, nanopores have been a promising technology for next generation deoxyribonucleic acid (DNA) sequencing. As single-stranded DNA translocates through a nanopore, each nucleotide induces a blockage in the ionic channel, creating a unique current signature. However, the fast translocation speed and small current changes, which are superimposed on a much larger baseline current,...
By 2015, there will be an estimated 2.03 billion smartphone users worldwide [1]. This wide spread availability of mobile computing has inspired a surge of peripheral devices that add health-oriented functionality to the smartphone, such as the iBGStar® blood glucose meter and the AliveCor® ECG monitor. By similarly leveraging the power and functionality of the smartphone, we have built an electronic...
This work presents a high sensitivity biosensing platform for quantitative proteomics. Biomolecules labeled with magnetic nanoparticle (MNP) tags are quantitatively sensed by a high density array of 256 giant magnetoresistive spin-valve (GMR SV) sensors connected to a 0.18 µm CMOS sensor interface featuring 16 ΣΔ modulators with 84 dB dynamic range. The performance of the system is demonstrated through...
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