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In this work we present a device able to electroporate and deliver molecules inside adherent cells using hollow nanoelectrodes that act also as nanofluidic channels. Our fabrication approach allows to greatly reduce the amplitude of the applied electrical pulse train and to selectively deliver molecules only to the targeted cells.
In natural environments commonly appear periodic micro- and nano-structures exhibiting macroscopic properties different from the ones on the single elements. Typical examples are butterfly wings in optics, lotus leaves in fluidics or complex 3D neuronal networks in neuroscience and biology. Within this context, mimicking the intrinsic regularity exhibited by natural architectures can lead to unprecedented...
In the study of neuronal networks or other cell cultures it is essential to combine information about a single element with the connections developed throughout the whole system. Those data come from different space and time scales, therefore requiring the employment of various techniques to be acquired and combined. Unfortunately, connecting data from more than one experiment is often challenging...
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