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Single photon emission computed tomography (SPECT) has the potential for quantitation of absolute activity concentration in vivo. The accuracy of activity estimates depends to a large extent on the accuracy of the attenuation and scatter corrections performed. This is particularly so in the thorax, where assumptions about regular object shape and constant density are inappropriate. We have developed...
In order to remove the influence of anaesthetic agents on neurological function and to expand the range of imaging tasks available it is preferable to image small animals in an awake state. Accurate activity estimates in awake small animal Positron Emission Tomography rely on the measurement of animal head pose over the time-course of the scan. Pose measurements are then incorporated into the emission...
Stereo optical motion tracking has been shown to b e a feasible and accurate way of measuring head pose in positron emission tomography (PET) studies of minimally restrained awake animals. The aim of this work was to determine the number and arrangement of binocular trackers to optimize continuity of head tracking for a freely moving animal. We established a performance criterion for continuous tracking...
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