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A behavioral model, based on Finite Elements and Partial Differential Eduation, of a impedance-based measurement system for assessing the drug released under the skin transdermal delivery is proposed. The model simulates: (i) the measurement system, based on Electrochemical Impedance Spectroscopy, (ii) the measurand, namely the drug delivered under the skin, as well as (iii) the system under test,...
An experimental procedure for measuring the drug absorbed by a biological tissue in laboratory emulation of dermatological topical treatments is proposed. Laboratory emulation is based on the analysis of the eggplant electrical reaction to the injection of drug. Eggplant and human tissue are both well modeled by a distributed circuit model described by the ColeCole empirical equation. An exploratory...
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