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Background Venous thromboembolism (VTE) in young children is not well documented. Methods Clinicians from 12 institutions retrospectively evaluated the presentation, therapeutic management, and outcome of VTE in children younger than 2 years seen in 2011–2016. Feasibility of recruiting these children in EINSTEIN-Jr. phase III, a randomized trial evaluating rivaroxaban versus standard anticoagulation...
Clock grid is a mainstream clock network methodology for high performance microprocessor and SOC designs. Clock skew, power usage and robustness to PVT (power, voltage, temperature) are all important metrics for a high quality clock grid design. Tree-driven-grid clock network is a typical clock grid clock network. It includes a clock source, a buffered tree, leaf buffers, a mesh clock grid, local...
Atypical antipsychotic long-acting injectables (LAIs) such as paliperidone palmitate (PP) are believed to provide a favorable safety profile compared with typical LAIs. Because no trials have compared PP directly with typical LAIs, we assessed the benefit–risk of PP relative to typical LAIs using published placebo-controlled trials.A computerized search in MEDLINE was conducted. Number needed to treat...
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