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In protein-protein interaction networks, proteins combine into macromolecular complexes to execute essential functions in the cells, such as replication, transcription, protein transport. Considering the certain rate of false positive and false negative interactions, we take a confidence probability on interactions and correlate interactions and gene expression data to assign weights to edges in PPI...
In protein-protein interaction networks, proteins combine into macromolecular complexes to execute essential functions in the cells, such as replication, transcription, protein transport. To solve the problem of detecting protein complexes from protein interaction networks, we use relevant graph and irrelevant graph to represent the relation of connection between a node and a core graph. We define...
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