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Cannabinoid CB 1 receptor (CB 1 R) signaling has been shown to play a role in the regulation of addictive behavior. In the present study, our aim was to investigate whether the CB 1 R antagonist SLV330 could reduce ethanol and nicotine self-administration and cue-induced reinstatement of ethanol and nicotine seeking behavior in Wistar rats.In operant chambers, rats were learned...
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