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Obstructive sleep apnea (OSA) is a common sleep disorder found in 24% of adult men and 9% of adult women. Although continuous positive airway pressure (CPAP) has emerged as a standard therapy for OSA, a majority of patients are not tolerant to this treatment, largely because of the uncomfortable nasal air delivery during their sleep. Recent advances in wireless communication and advanced (“bigdata”)...
Obstructive sleep apnea (OSA) is a common sleep disorder found in 24% of adult men and 9% of adult women. Although continuous positive airway pressure (CPAP) has emerged as a standard therapy for OSA, a majority of patients are not tolerant to this treatment due to the uncomfortable nasal air delivery during their sleep. We introduce a Dirichlet process Gaussian Mixture (DPGM) model to predict the...
As cardiovascular disorders have emerged as the primary cause of human mortality, quantitative modeling of cardiovascular system, including the dynamic coupling among its chemical, electrical and pulmonary mechanisms, has evoked keen interest in the recent years. The current dynamic models have little clinical relevance because they cannot be correlated with the real-time signals from a human heart...
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