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The purpose of this study was to construct a stability study of nanoemulsion-based hydrogel formulation and evaluate the profile of the formulation that exhibits the best stability. Olive oil was chosen as oil phase of nanoemulsion due to its superiority as an emollient and it has good skin permeation capability. In this study, a series of nanoemulsion formulation was prepared based on the various...
Xanthone is one of the major bioactive secondary metabolites in Garcinia mangostana. A simple reversed-phase high performance liquid (RP-HPLC) which equipped with photodiode array detector has been developed to analyze xanthone in rat plasma. The rat plasma was treated with deproteining agent (DA) consists of acetonitrile: propanol (1:1), in the ratio of 2:1 (DA: samples). The mobile phase comprises...
In this present study, the palm oil nanoemulsion hydrogels were formulated and stability of palm oil nanoemulsion hydrogels were investigated. The nanoemulsion hydrogel formulations that passed through droplet size test were characterized for viscoelastic behaviour. The best formulation was the one with composition of 10% palm oil (5:1 PO:L1695), 4.67% glycerine, 0.5% Carbopol 934 and 82.83% de-ionised...
Levodopa (l-dopa), the metabolic precursor of dopamine, has primarily been used for the treatment of Parkinson's disease (PD). A reversed phase high performance liquid chromatography (RP-HPLC) method with UV-detection at room temperature has been developed for analysis of levodopa. The method entailed direct injection of rat plasma sample after deproteinization using acetonitrile — propanol (1:1)...
Four selected Malaysian honey namely Gelam, Nenas, Acacia and Tualang were studied to identify their physicochemical properties such as moisture content, electrical conductivity, total ash content, free acidity, pH, hydroxymethylfurfural (HMF), and sugar and diastase activity. The parameters were measured using methods recommended by International Honey Commission (IHC) and Council Directive (2001/110/EC)...
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