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This paper describes a direct coupled neural amplifier with active electrode offset suppression in order to avoid large coupling capacitors and complex chopper circuits. It describes a novel feedback scheme, where a low pass current mode feedback is applied to a regulated telescopic cascode amplifer, at the cascode nodes by using a modified transconductance block. This solution leads to fully differential...
In this paper, the ion-sensitive field-effect transistor (ISFET) performance in unmodified complementary metal–oxide–semiconductor is thoroughly studied in terms of transconductance, threshold voltage, offset, and drift for the dimension and shape effects. It is shown that by increasing the ISFET sensing area, decoupling capacitors—as a function of the perimeter of the gate extension metal layers—may...
This paper describes a novel integrated electrode interface for multi-polar stimulation of multi-electrode arrays. This interface allows for simultaneous stimulation using multiple electrodes configured as source or sink with different phase and amplitudes in order to perform field shaping inside the tissue. The system is designed in an high voltage 0.18 µm CMOS process with 8 channels. It features...
Artificial electrical stimulation of the peripheral nervous system is an established therapy for several pathologies and motor impairments. Therapeutic outcomes can be improved with targeted patterns of neural activation, but the required signal amplitudes to achieve this response exceed the limits for safe stimulation. This can lead to electrode corrosion and tissue damage. In this paper, we present...
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