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Immunological studies frequently analyze individual components (e.g., signaling pathways) of immune systems in a reductionist manner. In contrast, systems immunology aims to give a synthetic understanding of how these components function together as a whole. While immunological research involves in vivo and in vitro experiments, systems immunology research can also be conducted in silico. With an...
Cancer progression accompanies changes in cell adhesion characteristics, which is crucial for cancer cell invasion and metastasis. Drugs altering cell adhesion have been suggested as a possible therapeutic treatment for cancer. Tumor cell adhesion is thus an important topic of current investigation. Recently individual cell (agent)-based in silico tumor models have incorporated mathematical models...
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