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Vitamin K antagonist (VKA) therapy for stroke prevention in atrial fibrillation (AF) requires monitoring of the international normalized ratio (INR). We evaluated the agreement between two INR audit parameters, frequency in range (FIR) and proportion of time in the therapeutic range (TTR), using data from a global population of patients with newly diagnosed non‐valvular AF, the Global Anticoagulant...
Data provided by THEW was used to test QT gender differences. Three QT/RR models were used during analysis: a transfer function model (TRF), a model based on exponential weighting of RR intervals (EXP), and an EXP model with additive direct coupling with RR intervals (EXPDC). Data from 81 men and 73 women was analyzed. Women have a significantly higher QTc (p<;10-6), steeper GainL (QT/RR slope,...
The study presents a method for quantification of the respiratory effect on the thoracic impedance signal. We used measurements with 18 simultaneously scanning impedance signal locations. Elimination of breathing is based on the assumption that the neck and limb impedance signal measures only the variability in systemic blood pressure and is not affected by respiration. The results show approximately...
Five dynamic models of QT/RR coupling are tested on measurements of tilt table test at 19 healthy individuals. RMS of error signal (difference between measured and computed QT) and correlation coefficient (R) between error signal and RR are analyzed. Four models were based on weighted average of RR intervals-constant weighting, exponential weighting with linear dependency and nonlinear dependency...
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