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Magnetic field inhomogeneity is a long-standing problem in magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI). Specifically, in MRSI, field inhomogeneity, if not corrected, can cause frequency shifts, line broadening, and lineshape distortions in the spectral peaks. This paper addresses the problem of correcting the field inhomogeneity effects on limited k-space MRSI data. A penalized...
Regularization is a common technique used to improve image quality in inverse problems such as MR image reconstruction. In this work, we extend our previous Graphics Processing Unit (GPU) implementation of MR image reconstruction with compensation for susceptibility-induced field inhomogeneity effects by incorporating an additional quadratic regularization term. Regularization techniques commonly...
In vivo diffusion tensor imaging measurements of the mouse brain stem and cervical spinal cord are presented. Utilizing actively decoupled transmit/receive coils, high resolution diffusion images (117μm×59μm×500μm) were acquired at 4.7T within an hour. Both brain stem and cervical spine displayed clear gray-white matter contrast. The cervical spinal cord white matter showed similar tissue characteristics...
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