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This paper presents a 22-bit time-interpolated Time-to-Digital Converter (TDC) with 110ps temporal resolution for biochemical sensing applications, which utilize time-resolve luminescence imaging technique. The TDC achieves wide dynamic range operation by incorporating a hybrid architecture that combines a 14-bit digital counter based coarse TDC and an 8-bit Voltage-Controlled Delay Line (VCDL) based...
This letter presents an integrated complementary metal-oxide semiconductor fluorometer that utilizes frequency-domain fluorescence lifetime imaging spectroscopy for oxygen-sensing applications. The implemented fluorometer chip consists of a -well/p-substrate photodiode, a phase readout circuit with integrated zero-crossing detection to extract the frequency-domain phase shift into...
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