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Various approaches have been proposed to identify malignant breast tumors using ultrasound. In this study, we implement three different approaches and one combined method. Performance of these approaches is investigated based on simulation data. The three approaches are: video signal analysis (VSA), spectral estimation using periodogram (PER), and minimum side difference (MSD). Note that all approaches...
Acoustic, texture, and morphological features of the breast in ultrasound imaging were extracted for computer-aided diagnosis. In addition, correlations among different categories of features were analyzed. Clinical data from 14 patients (7 malignant and 7 benign samples) were acquired. A custom-made setup was used for simultaneous data acquisition of B-mode ultrasound and limited-angle tomography...
Sound-velocity inhomogencities degrade both the spatial resolution and the contrast in diagnostic ultrasound. We previously proposed an adaptive imaging approach based on the coherence of the data received in the channels of a transducer array, and we tested it on phantom data. In this study, the approach was tested on clinical breast data and compared with a correlation-based method that has been...
The aim of this study was to determine the efficacy of using the sound velocity and tissue attenuation to clinically discriminate breast cancer from healthy tissues. The methods for reconstructing the sound-velocity and attenuation-coefficient distributions were previously proposed and tested on tissue-mimicking phantoms. The methods require only raw channel data acquired by a linear transducer array,...
Sound-velocity inhomogeneities degrade both the spatial resolution and the contrast in diagnostic ultrasound. We previously proposed an adaptive imaging approach based on the coherence of the data received in the channels of a transducer array, and tested it on phantom data. In this study the approach was tested on clinical breast data, and compared with a correlation-based method that has been widely...
Tumor volume measurement on small animals is important but currently invasive. We employ ultrasonic micro-imaging (UMI) in this study and demonstrate its feasibility. In addition, we use small animal positron emission tomography (microPET) as a preliminary effort to develop multi-modality small animal imaging techniques. The tumor growth curve from UMI is also compared to radioactivity from microPET...
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