Search results for: A. Abraham

Items from 1 to 20 out of 566 results

article

Characterization of polyhydroxybutyrate production from Halomonas titanicae KHS3 and manufacturing of electrosprayed nanoparticles

Ailén N. Rodríguez, Mariana Escobar, Ingrid E. Redersdorff, Claudia A. Studdert, more

Journal of Applied Polymer Science > 141 > 6 > n/a - n/a

Polyhydroxyalkanoates (PHAs) are biopolymers accumulated by a diversity of bacterial strains as carbon and energy reserve when grown under unbalanced nutritional conditions. Among the wide spectrum of applications for these biopolymers, the generation of nano and microparticles has drawn huge attention. PHA nanoparticles showed a high surface‐to‐volume ratio that makes them interesting for pharmaceutical...

article

OA2‐AM23‐ST‐23 | Early Convalescent Plasma Treatment Reduces Inflammation After Symptomatic COVID‐19

X. Zhu, F. Habtehyimer, K. Gebo, A. Abraham, more

Transfusion > 63 > S5 > 32A - 33A

article

Human adipose mesenchymal stromal cells growing into PCL‐nHA electrospun scaffolds undergo hypoxia adaptive ultrastructural changes

Yesica R. Frontini‐López, Lautaro Rivera, Ana A. Aldana, Guadalupe Rivero, more

Biotechnology Journal > 18 > 4 > n/a - n/a

Human Adipose‐Derived Mesenchymal Stem/Stromal Cells (hAD‐MSCs) have great potential for tissue regeneration. Since transplanted hAD‐MSCs are likely to be placed in a hypoxic environment, culturing the cells under hypoxic conditions might improve their post‐transplantation survival and regenerative performance. The combination of hAD‐MSCs and PCL‐nHA nanofibers synergically improves the contribution...

article

Breast cancer incidence among women with a family history of breast cancer by relative's age at diagnosis

Danielle D. Durham, Linn A. Abraham, Megan C. Roberts, Carly P. Khan, more

Cancer > 128 > 24 > 4232 - 4240

Background Women with a first‐degree family history of breast cancer are often advised to begin screening when they are 10 years younger than the age at which their relative was diagnosed. Evidence is lacking to determine how much earlier they should begin. Methods Using Breast Cancer Surveillance Consortium data on screening mammograms from 1996 to 2016, the authors constructed a cohort of 306,147...

article

Metagenomic signature and total petroleum hydrocarbons distribution in a crude oil contaminated ultisol remediated with biochar–humus sediment slurry

Nnanake‐Abasi O. Offiong, Edu J. Inam, Opeyemi K. Fatunla, Utibe A. Ofon, more

Remediation Journal > 32 > 4 > 299 - 308

Ultisols are peculiar soils generally known for their poor nutrient status. When contaminated, remediation of ultisols present the additional challenge of nutrient and ecological restoration. In this study, we report the distribution of total petroleum hydrocarbons (TPHs) in a simulated crude oil‐contaminated ultisol amended with biochar (BC)/humus sediment (HS) slurry. We also investigated the microbial...

article

Additive manufacturing of bioresorbable poly(ester‐urethane)/glass‐ceramic composite scaffolds

Nayla J. Lores, Xavier Hung, Mariano H. Talou, Josefina Ballarre, more

Polymer Composites > 43 > 8 > 5611 - 5622

The development of three‐dimensionally printed implants for biomaterial‐based tissue engineering applications is currently an active research field. In order to meet the requirements of several applications, new biocompatible and bioresorbable polymer‐based materials are needed to design tailor‐made polymer/composite scaffolds. In the last decade, bioresorbable segmented poly(ester‐urethanes) (SPEU)...

article

Limited utility of plasma elafin as a biomarker for skin graft‐versus‐host disease following allogeneic stem cell transplantation

L. George, G. Mahabal, E. Mohanan, P. Balasubramanian, more

Clinical and Experimental Dermatology > 46 > 8 > 1482 - 1487

Background Acute cutaneous graft‐versus‐host disease (acGVHD) following haematopoietic stem cell transplant (HSCT) is common but difficult to distinguish from other causes of rash. Plasma elafin has been proposed as a diagnostic and prognostic biomarker of skin GVHD. Aim To evaluate the role of plasma elafin as a biomarker in acGVHD in an Indian population. Methods Plasma elafin was evaluated...

article

A modular platform based on electrospun carbon nanofibers and poly(N‐isopropylacrylamide) hydrogel for sensor applications

Silvestre Bongiovanni Abel, María V. Martinez, Mariano M. Bruno, Cesar A. Barbero, more

Polymers for Advanced Technologies > 32 > 12 > 4815 - 4825

Modular sensor platforms are a fashion approach that allows the use of advanced materials to promote the evolution of portable electrochemical sensors. A modular platform building by the combination of carbonized poly(acrylonitrile) electrospun mat (C‐PAN; fiber diameter ca. 300 nm) and a poly(N‐isopropylacrylamide; PNIPAm) hydrogel was assayed. The individual components of the platform were physicochemically...

article

SMARCA2‐NR4A3 is a novel fusion gene of extraskeletal myxoid chondrosarcoma identified by RNA next‐generation sequencing

Shuanzeng Wei, Jianming Pei, Margaret von Mehren, John A. Abraham, more

Genes, Chromosomes and Cancer > 60 > 10 > 709 - 712

Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain differentiation, characterized by recurrent chromosomal translocation involving NR4A3 (9q22.33) in more than 90% of cases. Five fusion partners for NR4A3 have been described including: EWSR1 (22q12.2), TAF15 (17q12), FUS (16p11.2), TCF12 (15q21), and TFG (3q12.2). This report describes a patient with an EMC at the dorsum of the...

article

Novel three‐dimensional printing of poly(ester urethane) scaffolds for biomedical applications

Nayla J. Lores, Xavier Hung, Mariano H. Talou, Gustavo A. Abraham, more

Polymers for Advanced Technologies > 32 > 8 > 3309 - 3321

Tissue engineering requires highly porous complex structures with interconnected pores and tightly controlled pore sizes, added to customized production. Additive manufacturing (AM) is nowadays one of the most suitable technologies for the preparation of structures with strictly defined complex three‐dimensional architectures. Moreover, computed tomography and magnetic resonance imaging can be employed...

article

PROGNOSTIC SIGNIFICANCE OF TIME FROM LAST THERAPY IN PATIENTS WITH DIFFUSE LARGE B‐CELL LYMPHOMA: RETROSPECTIVE ANALYSIS OF ELECTRONIC HEALTH RECORDS AND CLAIMS DATA IN THE US

M. Matasar, F. Castro, Y. Liu, A. Abraham, more

Hematological Oncology > 39 > S2 > n/a - n/a

article

Employing supervised classification techniques in determining playability status of polyester‐urethane magnetic audio tapes

Nathan C. Fuenffinger, Nilmini H. Ratnasena, Brianna M. Cassidy, Zhenyu Lu, more

Journal of Chemometrics > 35 > 4 > n/a - n/a

As magnetic audio tapes age, various chemical and physical degradation processes can affect the playability of the tapes. The extent that a tape is degraded, however, is often difficult to observe without actually playing the tape. Attempting to play an extensively degraded tape can result in damage to the tape as well as to the instrument used to play the tape. Our recent work has focused on less...

article

Initial impact of COVID‐19 on dialysis provision; review of international guidelines and adaptation of a hub unit's service

Terry Simons, Andrew MacGlashan, Christopher Goldsmith, Harsha Wodeyar, more

Seminars in Dialysis > 34 > 2 > 123 - 129

The COVID‐19 pandemic has put a strain on many aspects of health care including the provision of dialysis. Two categories of patients have had the greatest impact on dialysis capacity. Those with COVID‐19‐related acute kidney injury and those chronic dialysis patients who required isolation or cohort dialysis because of the pandemic. Limited information on incidence hampers capacity planning and the...

article

Hematopoietic stem cell transplant referral patterns for children with sickle cell disease vary among pediatric hematologist/oncologists’ practice focus: A Sickle Cell Transplant Advocacy and Research Alliance (STAR) study

Emily Riehm Meier, Allistair A. Abraham, Alex Ngwube, Isaac A. Janson, more

Pediatric Blood & Cancer > 68 > 3 > n/a - n/a

Background Hematopoietic stem cell transplantation (HSCT) provides a curative therapy for children severely affected by sickle cell disease (SCD). Rejection‐free survival after matched sibling donor (MSD) HSCT is very high, but adoption of HSCT as a curative SCD therapy has been slow. In this study, we assess providers’ perceptions about MSD HSCT for children with variable SCD severity, and determine...

article

Incidence, Risk Factors for and Outcomes of Transplant‐Associated Thrombotic Microangiopathy

Narendranath Epperla, Ang Li, Brent Logan, Caitrin Fretham, more

British Journal of Haematology > 189 > 6 > 1171 - 1181

Transplant‐associated thrombotic microangiopathy (TA‐TMA) is a complication of allogeneic transplantation (allo‐HCT). The incidence and risk factors associated with TA‐TMA are not well known. A retrospective analysis from the Center for International Blood and Marrow Transplant Research (CIBMTR) was conducted including patients receiving allo‐HCT between 2008 and 2016, with the primary objective of...

article

Survival and Prognosis of Chondrosarcoma Subtypes: SEER Database Analysis

Kamil M. Amer, Murty Munn, Dominick Congiusta, John A. Abraham, more

Journal of Orthopaedic Research® > 38 > 2 > 311 - 319

Chondrosarcomas are rare tumors and, historically, investigation of these tumors has been limited to small series and single‐institution studies. There have been no studies that evaluated the identification or comparison of differences in prognostic factors between the five known non‐conventional chondrosarcoma subtypes (myxoid, juxtacortical, clear‐cell, mesenchymal, and dedifferentiated). The purpose...

article

Chronic stress, depression and personality type in patients with myasthenia gravis

A. Bogdan, C. Barnett, A. Ali, M. AlQwaifly, more

European Journal of Neurology > 27 > 1 > 204 - 209

Background and purpose Stress is a known risk factor for the onset and modulation of disease activity in autoimmune disorders. The aim of this cross‐sectional study was to determine any associations between myasthenia gravis (MG) severity and chronic stress, depression and personality type. Methods In all, 179 consecutive adult patients with confirmed MG attending the Neuromuscular Clinic between...

article

Core–sheath nanofibrous membranes based on poly(acrylonitrile‐butadiene‐styrene), polyacrylonitrile, and zinc oxide nanoparticles for photoreduction of Cr(VI) ions in aqueous solutions

Andrés Castro‐Ruíz, Heriberto Rodríguez‐Tobías, Gustavo A. Abraham, Guadalupe Rivero, more

Journal of Applied Polymer Science > 137 > 9 > n/a - n/a

This investigation addresses the design of a series of poly(acrylonitrile‐butadiene‐styrene)/polyacrylonitrile–zinc oxide(ABS/PAN–ZnO) membranes by coaxial electrospinning. In the first instance, an optimization of ABS and PAN electrospinning was performed, thus establishing suitable compositional and processing parameters for obtaining homogenous fibers. Then, coaxial electrospinning of ABS and PAN...

article

Altered muscle electrical tissue properties in a mouse model of premature aging

Joanne Clark‐Matott, Janice A. Nagy, Benjamin Sanchez, Rebecca Taylor, more

Muscle & Nerve > 60 > 6 > 801 - 810

Introduction Improved methods are needed to detect and quantify age‐related muscle change. In this study we assessed the electrical properties of muscle impacted by acquired mitochondrial DNA mutations via the PolG mouse, which exhibits typical age‐associated features, and the impact of a potential therapy, nicotinamide mononucleotide (NMN). Methods The gastrocnemii of 24 PolG and 30 wild‐type...

article

A novel vaccine platform using glucan particles for induction of protective responses against Francisella tularensis and other pathogens

A. Abraham, G. Ostroff, S. M. Levitz, P. C. F. Oyston

Clinical & Experimental Immunology > 198 > 2 > 143 - 152

Vaccines are considered the bedrock of preventive medicine. However, for many pathogens, it has been challenging to develop vaccines that stimulate protective, long‐lasting immunity. We have developed a novel approach using β‐1,3‐D‐glucans (BGs), natural polysaccharides abundantly present in fungal cell walls, as a biomaterial platform for vaccine delivery. BGs simultaneously provide for receptor‐targeted...

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INFONA - science communication portal

Search results for: A. Abraham

Characterization of polyhydroxybutyrate production from Halomonas titanicae KHS3 and manufacturing of electrosprayed nanoparticles

OA2‐AM23‐ST‐23 | Early Convalescent Plasma Treatment Reduces Inflammation After Symptomatic COVID‐19

Human adipose mesenchymal stromal cells growing into PCL‐nHA electrospun scaffolds undergo hypoxia adaptive ultrastructural changes

Breast cancer incidence among women with a family history of breast cancer by relative's age at diagnosis

Metagenomic signature and total petroleum hydrocarbons distribution in a crude oil contaminated ultisol remediated with biochar–humus sediment slurry

Additive manufacturing of bioresorbable poly(ester‐urethane)/glass‐ceramic composite scaffolds

Limited utility of plasma elafin as a biomarker for skin graft‐versus‐host disease following allogeneic stem cell transplantation

A modular platform based on electrospun carbon nanofibers and poly(N‐isopropylacrylamide) hydrogel for sensor applications

SMARCA2‐NR4A3 is a novel fusion gene of extraskeletal myxoid chondrosarcoma identified by RNA next‐generation sequencing

Novel three‐dimensional printing of poly(ester urethane) scaffolds for biomedical applications

PROGNOSTIC SIGNIFICANCE OF TIME FROM LAST THERAPY IN PATIENTS WITH DIFFUSE LARGE B‐CELL LYMPHOMA: RETROSPECTIVE ANALYSIS OF ELECTRONIC HEALTH RECORDS AND CLAIMS DATA IN THE US

Employing supervised classification techniques in determining playability status of polyester‐urethane magnetic audio tapes

Initial impact of COVID‐19 on dialysis provision; review of international guidelines and adaptation of a hub unit's service

Hematopoietic stem cell transplant referral patterns for children with sickle cell disease vary among pediatric hematologist/oncologists’ practice focus: A Sickle Cell Transplant Advocacy and Research Alliance (STAR) study

Incidence, Risk Factors for and Outcomes of Transplant‐Associated Thrombotic Microangiopathy

Survival and Prognosis of Chondrosarcoma Subtypes: SEER Database Analysis

Chronic stress, depression and personality type in patients with myasthenia gravis

Core–sheath nanofibrous membranes based on poly(acrylonitrile‐butadiene‐styrene), polyacrylonitrile, and zinc oxide nanoparticles for photoreduction of Cr(VI) ions in aqueous solutions

Altered muscle electrical tissue properties in a mouse model of premature aging

A novel vaccine platform using glucan particles for induction of protective responses against Francisella tularensis and other pathogens

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