The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Objective: Metabolic enzymes and biotransformation of paeonol were studied by extraorgan incubation method in homogenized liver, and rational clinical administration method of paeonol was provided with scientific evidences. Methods: The content of surplus paeonol in the homogenized liver incubation solution was detected by HPLQ, and the effects of inductors and inhibitors in metabolism of paeonol...
Toluene diisocyanate was a kind of indoor air pollutant with low toxic, but the most toxic in all diisocyanate esters, which was recognized as a kind of industry allergen. To study the effect on markers of oxidative damage and energy metabolism in blood induced by toluene diisocyanate(TDI). The mice contacted with TDI by respiratory tract in 50L static inhalation tank. The Exposure sustained two weeks,...
To identify the chemical constituents in Jinkuishenqi pills metabolized in vivo. Analysis and comparison were carried out by LC- ESI-MS among rats' serum samples obtained after oral administration of different ingredient preparations such as Jinkuishenqi pills , Jinkuishenqi Pills without one of ingredients and single ingredient crude drug and control serum. The compounds absorbed into blood , their...
This paper is to determine metabolites of toluene diisocyanate (TDI) in mice and deduced the pathway for toluene diisocyanate metabolism in the organism. Toluene diisocyanate was administered to mice for 2 weeks, samples of blood, feces, and urine were taken, and the structure of the toluene diisocyanate metabolites was determined using gas chromatography-mass spectrometry (GC-MS). Conditions for...
This paper is to to determine metabolites of toluene diisocyanate (TDI) in mice and deduced the pathway for toluene diisocyanate metabolism in the organism. Toluene diisocyanate was administered to mice for 2 weeks, samples of blood, feces, and urine were taken, and the structure of the toluene diisocyanate metabolites was determined using gas chromatography-mass spectrometry (GC-MS). Conditions for...
This paper is to study the effects of TDI on mice marrow cells . The effects of TDI were studied by laser scanning confocal microscope to investigate morphologic changing of the mice bone marrow cell and genotoxicity test -chromosomal aberration test and sister chromatic exchange (SCE) test. Results showed that the 1/16LC50 and 1/8LC50 dosage of TDI had no significant effects on the fluorescence pixels...
To study the effects of two kinds of cactus polysaccharides on band 3 protein content, cross-linking protein content, and the lipid fluidity of erythrocyte membrane in S180 mice. Membrane protein content is analyzed by SDS-PAGE, and lipid fluidity of the membrane is measured by the Skinitzky method. The two kinds of cactus polysaccharide increase the content of band 3 protein, decrease the content...
To observe the effect of solanine on the contents of caspase-3 and Bcl-2 in HepG2 , and to explicate the mechanism by which solanine induces the apoptosis of tumor cells.Laser confocal scanning microscopy (LCSM) and Western blot were used to measure the contents of caspase-3 and Bcl-2 , and LCSM was used to determine their locations in the cell. Solanine markedly increased the content of caspase-3...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.