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While the aberrant translocation of the mixed-lineage leukemia (MLL) gene drives pathogenesis of acute myeloid leukemia (AML), it represents an independent predictor for poor prognosis of adult AML patients. Thus, small molecule inhibitors targeting menin-MLL fusion protein interaction have been emerging for the treatment of MLL-rearranged AML. As both inhibitors of histone deacetylase (HDAC) and...
In this paper, robust stabilization problems for Networked Control System (NCS) with data loss are investigated. We treat the data dropouts caused by network transmission data rate limit as a switch and obtain the discrete-time linear stochastic switch model for NCS. The stability analysis of closed-loop NCS with data dropout is studied, and a robust Hinfin state feedback controller is designed to...
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