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The benefit of pulsatile perfusion during cardiopulmonary bypass is still controversial.In this study we examined the non-pulsatile perfusion generated by a roller pump, the pulsatile perfusion induced by a roller- pump and the "physiological" pulsatile perfusion generated by a new device on renal and gut tissue perfusion, haemolysis and inflammatory response.In the group with the new computer-controlled...
Objective: Operations coupled with cardiopulmonary bypass may provoke a systemic inflammatory response, and it has been suggested that this responses causes capillary leakage of proteins, edema formation, and even organ failure. However, capillary leak syndrome is mainly a clinical diagnosis and has not been verified as yet by actual demonstration of protein leakage from the circulation. We have therefore...
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