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Outsourcing IT support of an enterprise requires that third level IT support is provided as a service by the outsourcer. Although there is a large body of existing work regarding demand forecasting and shift schedule creation for various domains such as call centers, very little work exists for third level IT support. Moreover, there is a significant difference between such support and other types...
Component business modeling (CBM) serves as a powerful analytical framework for reasoning about the business as a set of business components that collaborate through the provision and consumption of business services. This paper proposes and illustrates a method to calculate the relative importance of the entities that make up a componentized enterprise architecture. The proposed method includes a...
Following immunological insult, T cells migrate from blood vessels to inflammatory sites through the extracellular matrix (ECM). This movement is regulated by signals provided by proinflammatory mediators, including cytokines, chemokines and ECM-degrading enzymes. Here, Dalia Gilat and colleagues discuss the interactions between tissue-invading T cells and locally secreted, diffusible or ECM-anchored...
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