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Electrocardiographic (ECG) ST segment shifts are often used as markers for detecting myocardial ischemia. Literature suggests that the progression of ischemia, occurs from the endocardium and spreads towards the epicardium, eventually becoming transmural. Our study with animal models has found the progression of ischemia, characterized by ST elevations to be more complex and heterogeneous in its distribution...
Recent development and dissemination of effective and highly automated devices for internal and external defibrillation have impacted the prognosis of sudden cardiac arrest. Evidence for the efficacy and safety and energy dosing of defibrillating devices is based largely on clinical experience in adults, but children and patients with congenital heart disease may have issues of body size and/or cardiac...
Computational modeling and simulation can provide important insights into the electrical and electrophysiological properties of cells, tissues, and organs. Commonly, the modeling is based on Maxwell's and Poisson's equations for electromagnetic and electric fields, respectively, and numerical techniques are applied for field calculation such as the finite element and finite differences methods. Focus...
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