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The oleo-resin from Copaifera langsdorffii (Leguminosae) was evaluated in rats on acetic acid-induced colitis. Rats were pretreated orally (15 and 2h) or rectally (2h) before the induction of colitis with copaiba oleo-resin (200 and 400mg/kg) or vehicle (1ml, 2% Tween 80). Colitis was induced by intracolonic instillation of a 2ml of 4% (v/v) acetic acid solution and 24h later, the colonic mucosal...