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Calcium signaling in the diverse vascular structures is regulated by a wide range of mechanical and biochemical factors to maintain essential physiological functions of the vasculature. To properly transmit information, the intercellular calcium communication mechanism must be robust against various conditions in the cellular microenvironment. Using plasma lithography geometric confinement, we investigate...
Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography...
We have utilized a plasma based patterning technique, that we have developed, to study the effects of micrometer and submicrometer scale surface functionalization on cell proliferation and morphology. We have applied this method to cellular patterning and examined the response of mammalian cells to patterns of hydrophobic and hydrophilic areas created directly on polystyrene substrates. We have observed...
Template-guided self-assembly is one of the most promising approaches for creating functional nanosystems and effective methods are needed in order to generate micro and nanoscale templates for a diverse type of materials necessary for different applications. In this paper a plasma lithography technique is demonstrated which can directly pattern a wide variety of substrates including polystyrene,...
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