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Iron toxicity is the major cause of tissue damage in patients with iron overload. Iron deposits mainly in the liver, where its concentration closely correlates with whole body iron overload. Different techniques have been proposed for estimating iron content, with liver biopsy being the gold standard despite its invasiveness and influence by sampling error. Recently, magnetic resonance imaging (MRI)...
Iron toxicity is the major factor for tissue damage and organ failure in patients with iron overload. T2∗ measurement with magnetic resonance imaging (MRI) has been established as an effective and non-invasive technique for evaluating iron content in the liver. However, different factors related to the adopted image processing criterion affect the resulting measurements. These factors include the...
Iron toxicity is a key factor for tissue damage in iron-overloaded patients, with induced heart failure being the main cause of death. T2∗-weighted magnetic resonance imaging (MRI) has been established as the method of choice for evaluating iron content with strong correlation with biopsy, where T2∗ < 20 ms and T2∗ < 10 ms at 1.5T indicate iron overload and severe iron overload, respectively...
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