Search results for: Peter H. Weiss

Items from 1 to 20 out of 46 results

article

Deficient allo‐centric visuospatial processing contributes to apraxic deficits in sub‐acute right hemisphere stroke

Simon D. Ubben, Gereon R. Fink, Stephanie Kaesberg, Elke Kalbe, more

Journal of Neuropsychology > 14 > 2 > 242 - 259

While visuospatial deficits are well‐characterized cognitive sequelae of right hemisphere (RH) stroke, apraxic deficits in RH stroke remain poorly understood. Likewise, very little is known about the association between apraxic and visuospatial deficits in RH stroke or about the putative common or differential pathophysiology underlying these deficits. Therefore, we examined the behavioural and lesion...

article

Anodal tDCS over left parietal cortex expedites recovery from stroke-induced apraxic imitation deficits: a pilot study

Jana M. Ant, Eva Niessen, Elisabeth I. S. Achilles, Jochen Saliger, more

Neurological Research and Practice > 2019 > 1 > 1 > 1-10

Background To date, specific therapeutic approaches to expedite recovery from apraxic deficits after left hemisphere (LH) stroke remain sparse. Thus, in this pilot study we evaluated the effect of anodal transcranial direct current stimulation (tDCS) in addition to a standardized motor training on apraxic imitation deficits. Methods In a rehabilitation hospital, we assessed apraxic, aphasic, and...

article

Action and semantic tool knowledge – Effective connectivity in the underlying neural networks

Nina N. Kleineberg, Anna Dovern, Ellen Binder, Christian Grefkes, more

Human Brain Mapping > 39 > 9 > 3473 - 3486

Evidence from neuropsychological and imaging studies indicate that action and semantic knowledge about tools draw upon distinct neural substrates, but little is known about the underlying interregional effective connectivity. With fMRI and dynamic causal modeling (DCM) we investigated effective connectivity in the left‐hemisphere (LH) while subjects performed (i) a function knowledge and (ii) a value...

article

Using multi-level Bayesian lesion-symptom mapping to probe the body-part-specificity of gesture imitation skills

Elisabeth I.S. Achilles, Peter H. Weiss, Gereon R. Fink, Ellen Binder, more

NeuroImage > 2017 > 161 > C > 94-103

Past attempts to identify the neural substrates of hand and finger imitation skills in the left hemisphere of the brain have yielded inconsistent results. Here, we analyse those associations in a large sample of 257 left hemisphere stroke patients. By introducing novel Bayesian methods, we characterise lesion symptom associations at three levels: the voxel-level, the single-region level (using anatomically...

article

Timing independent spatial motor sequence learning is preserved in left hemisphere stroke

Anna Dovern, Eva Niessen, Jana M. Ant, Jochen Saliger, more

Neuropsychologia > 2017 > 106 > C > 322-327

During neurorehabilitation, the re-learning of motor sequences is crucial for patients with motor deficits, enabling them to master again complex movements. A recent study showed that patients with left hemisphere (LH) stroke exhibited preserved motor sequence learning (as assessed by the serial reaction time (SRT) task) when the timing of the stimuli was comparable in the training and later test...

article

Error detection across the adult lifespan: Electrophysiological evidence for age-related deficits

Eva Niessen, Gereon R. Fink, Heide E.M. Hoffmann, Peter H. Weiss, more

NeuroImage > 2017 > 152 > C > 517-529

With increasing age, cognitive control processes steadily decline. Prior research suggests that healthy older adults have a generally intact performance monitoring system, but show specific deficits in error awareness, i.e., the ability to detect committed errors. We examined the neural processing of errors across the adult lifespan (69 participants; age range 20–72 years) by analysing the error (-related)...

article

Lesion evidence for a human mirror neuron system

Ellen Binder, Anna Dovern, Maike D. Hesse, Markus Ebke, more

Cortex > 2017 > 90 > C > 125-137

More than two decades ago, the mirror neuron system (MNS) was discovered in non-human primates: Single-cell recordings detected visuo-motor neurons that discharged not only when the monkey performed an action, but also when it observed conspecifics performing the same action. It has been proposed that a fronto-parietal circuitry constitutes the human homolog of the MNS. However, the functional role...

article

Where language meets meaningful action: a combined behavior and lesion analysis of aphasia and apraxia

Peter H. Weiss, Simon D. Ubben, Stephanie Kaesberg, Elke Kalbe, more

Brain Structure and Function > 2016 > 221 > 1 > 563-576

It is debated how language and praxis are co-represented in the left hemisphere (LH). As voxel-based lesion-symptom mapping in LH stroke patients with aphasia and/or apraxia may contribute to this debate, we here investigated the relationship between language and praxis deficits at the behavioral and lesion levels in 50 sub-acute stroke patients. We hypothesized that language and (meaningful) action...

article

Deficits of reach-to-grasp coordination following stroke: Comparison of instructed and natural movements

Benjamin Baak, Otmar Bock, Anna Dovern, Jochen Saliger, more

Neuropsychologia > 2015 > 77 > C > 1-9

The present work evaluates whether stroke-induced deficits of reach-to-grasp movements, established by typical laboratory paradigms, transfer unconditionally to more natural situations.Sixteen patients with a stroke to the motor-dominant left hemisphere and 16 age- and gender-matched healthy control subjects executed grasping movements with their left (ipsilesional, non-dominant) hand. All movements...

article

Apraxia and spatial inattention dissociate in left hemisphere stroke

David C. Timpert, Peter H. Weiss, Simone Vossel, Anna Dovern, more

Cortex > 2015 > 71 > C > 349-358

Theories of lateralized cognitive functions propose a dominance of the left hemisphere for motor control and of the right hemisphere for spatial attention. Accordingly, spatial attention deficits (e.g., neglect) are more frequently observed after right-hemispheric stroke, whereas apraxia is a common consequence of left-hemispheric stroke. Clinical reports of spatial attentional deficits after left...

article

Subthalamic nucleus stimulation improves Parkinsonian gait via brainstem locomotor centers

Peter H. Weiss, Jan Herzog, Monika Pötter‐Nerger, Daniela Falk, more

Movement Disorders > 30 > 8 > 1121 - 1125

BackgroundSubthalamic deep brain stimulation (STN‐DBS) can ameliorate gait disturbances in Parkinson's disease (PD). Using motor imagery and positron emission tomography (PET), we investigated how STN‐DBS interacts with supraspinal locomotor centers in PD. MethodsTen PD patients with bilateral STN‐DBS actually walked or stood still under STN‐DBS ON or OFF conditions. Directly thereafter, subjects...

article

Implicit interactions between number and space in digit-color synesthesia

Eva Niessen, Gereon R. Fink, Lisa Schweitzer, Nora Kluender, more

Cortex > 2015 > 64 > Complete > 225-234

In digit-color synesthesia, a variant of grapheme-color synesthesia, digits trigger an additional color percept. Recent work on number processing in synesthesia suggests that colors can implicitly elicit numerical representations in digit-color synesthetes implying that synesthesia is bidirectional. Furthermore, morphometric investigations revealed structural differences in the parietal cortex of...

article

Anosognosia, neglect, extinction and lesion site predict impairment of daily living after right-hemispheric stroke

Simone Vossel, Peter H. Weiss, Philipp Eschenbeck, Gereon R. Fink

Cortex > 2013 > 49 > 7 > 1782-1789

Right-hemispheric stroke can give rise to manifold neuropsychological deficits, in particular, impairments of spatial perception which are often accompanied by reduced self-awareness of these deficits (anosognosia). To date, the specific contribution of these deficits to a patient's difficulties in daily life activities remains to be elucidated.In 55 patients with right-hemispheric stroke we investigated...

article

Imagined tool-use in near and far space modulates the extra-striate body area

Barbara Tomasino, Peter H. Weiss, Gereon R. Fink

Neuropsychologia > 2012 > 50 > 10 > 2467-2476

Active tool-use can result in the incorporation of the tool into the body schema, e.g., the representation of the arm is enlarged according to tool length. This modification even influences the processing of space: using a long tool leads to a remapping of far space as near space. We here further investigate the interaction of the neural representations of the human body, tool use, and spatial domain...

article

Functional synchronization in repetitive bimanual prehension movements

Marianne I. Christel, Marc Jeannerod, Peter H. Weiss

Experimental Brain Research > 2012 > 217 > 2 > 261-271

To examine the mechanisms of functional bimanual synchronization in goal-directed movements, we studied the movement kinematics of motorically unimpaired subjects while they performed repetitive prehension movements (either unimanually or bimanually) to small food items. Compared to unimanual conditions, bimanual movement execution yielded a significantly prolonged mouth contact phase. We hypothesized...

article

Visuo‐spatial representations of the alphabet in synaesthetes and non‐synaesthetes

Clare N. Jonas, Alisdair J.G. Taylor, Sam Hutton, Peter H. Weiss, more

Journal of Neuropsychology > 5 > 2 > 302 - 322

Visuo‐spatial representations of the alphabet (so‐called ‘alphabet forms’) may be as common as other types of sequence–space synaesthesia, but little is known about them or the way they relate to implicit spatial associations in the general population. In the first study, we describe the characteristics of a large sample of alphabet forms visualized by synaesthetes. They most often run from left to...

article

The neural basis of perceptual bias and response bias in the Landmark task

Simone Vossel, Philipp Eschenbeck, Peter H. Weiss, Gereon R. Fink

Neuropsychologia > 2010 > 48 > 13 > 3949-3954

Spatial neglect as a multifaceted syndrome may consist of perceptual/attentional as well as motor/intentional components. The present study investigated the lesion anatomy underlying perceptual and response bias using a manual response Landmark task (Bisiach, Ricci, Lualdi, & Colombo, 1998) in 68 patients with right-hemispheric stroke. The two differential aspects of the neglect syndrome were...

article

Testing for neglect in right-hemispheric stroke patients using a new assessment battery based upon standardized activities of daily living (ADL)

Philipp Eschenbeck, Simone Vossel, Peter H. Weiss, Jochen Saliger, more

Neuropsychologia > 2010 > 48 > 12 > 3488-3496

Spatial neglect is most frequently observed after right-hemispheric stroke and is characterized by a failure to report, to respond, or to orient to stimuli presented to the contralesional side. Although many neglect patients show difficulties in accomplishing activities of daily living (ADL), to date the clinical assessment of neglect is based upon neuropsychological paper-and-pencil tests. Thus,...

article

Specific role of medial prefrontal cortex in retrieving recent autobiographical memories: An fMRI study of young female subjects

Silvia Oddo, Silke Lux, Peter H. Weiss, Anna Schwab, more

Cortex > 2010 > 46 > 1 > 29-39

Episodic-autobiographical memory (AM) is characterized by self-conscious reflection, emotional connotation and mental time travel. Semantic memory (SM) contains context and emotion free general knowledge. The present study specifically aimed at exploring the effect of time on the neural substrates of autobiographical and semantic memory retrieval by studying memories from different life periods in...

article

Altered neural network supporting declarative long-term memory in mild cognitive impairment

Katrin Poettrich, Peter H. Weiss, Annett Werner, Silke Lux, more

Neurobiology of Aging > 2009 > 30 > 2 > 284-298

Autobiographical episodic memory represents a subsystem of declarative long-term memory and largely depends on combining information from multiple sources. The purpose of this study was to assess neural correlates of declarative long-term memory in patients with amnestic mild cognitive impairment (MCI) and controls using fMRI and a task requiring autobiographical and semantic memory retrieval. Comparison...

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Keywords

APRAXIA (7)
STROKE (6)
LANDMARK TASK (5)
FMRI (4)
MOTOR IMAGERY (3)
PARIETAL CORTEX (3)
VISUOSPATIAL NEGLECT (3)
VOXEL-BASED LESION-SYMPTOM MAPPING (3)
ATTENTION (2)
ATTENTIONAL MODULATION (2)
AUTOBIOGRAPHICAL MEMORY (2)
DEEP BRAIN STIMULATION (2)
EARLY VISUAL PROCESSING (2)
IMITATION (2)
LANGUAGE (2)
LINE BISECTION (2)
MOTOR SIMULATION (2)
NEGLECT (2)
NEUROREHABILITATION (2)
PARKINSON'S DISEASE (2)
RETROSPLENIAL CORTEX (2)
SEMANTICS (2)
SERIAL/PARALLEL PROCESSING (2)
SPATIAL BINDING (2)
VERBAL FLUENCY (2)
(INCIDENTAL) MOTOR LEARNING (1)
ACTION REPRESENTATIONS (1)
ACTION UNDERSTANDING (1)
ACTIVITIES OF DAILY LIVING (1)
AGING (1)
AIP (1)
AUTOMATIC SPEECH (1)
AWARENESS (1)
BAYESIAN (1)
BIMANUAL COORDINATION (1)
BODY SCHEMA (1)
BOLD (1)
BROCA’S REGION (1)
BRODMANN AREAS (1)
BRODMANN'S AREAS (1)
CALORIC STIMULATION (1)
CEREBELLUM (1)
CONTEXT-DEPENDENCE (1)
CYTOARCHITECTONIC STUDY (1)
DIRECTED ATTENTION (1)
DIRECTED ATTENTION TASK (1)
DORSAL AND VENTRAL STREAM (1)
DYNAMIC CAUSAL MODELING (1)
EEG (1)
EFFECTIVE CONNECTIVITY (1)
EMBODIED COGNITION (1)
EMOTION (1)
ERROR (-RELATED) NEGATIVITY (NE/ERN) (1)
ERROR POSITIVITY (PE) (1)
FUNCTIONAL IMAGING (1)
FUNCTIONAL SYNCHRONIZATION (1)
GRASPING (1)
GRIP FORCE (1)
HEMISPHERIC SPECIALISATION (1)
INTENTION (1)
JUDGEMENT (1)
KANIZSA FIGURES (1)
LATERAL OCCIPITO‐TEMPORAL CORTEX (1)
LEFT HEMISPHERE STROKE (1)
LESION (1)
LESION ANALYSIS (1)
LESION MAPPING (1)
LEXICAL RETRIEVAL (1)
LIMB APRAXIA (1)
LINE BISECTION TASK (1)
LOCOMOTION (1)
LONG-TERM MEMORY (1)
MEDIAL PREFRONTAL CORTEX (1)
MENTAL SIMULATION (1)
MESENCEPHALIC LOCOMOTOR REGION (1)
MILD COGNITIVE IMPAIRMENT (1)
MOTOR COGNITION (1)
MOTOR CONTROL (1)
MOTOR CORTEX (1)
MOTOR-RELATED VERBS (1)
NEUROANATOMY (1)
NEUROIMAGING (1)
NEUROMODULATION (1)
NEUROPSYCHOLOGICAL ASSESSMENT (1)
NEUROPSYCHOLOGY (1)
OCCIPITAL CORTEX (1)
OCCIPITO-TEMPORAL CORTEX (1)
PARALLEL ANALYSIS (PA) (1)
PARIETAL LOBE (1)
PEDUNCULOPONTINE NUCLEUS (1)
PERFORMANCE MONITORING (1)
PERSPECTIVE (1)
PET (1)
PREHENSION (1)
PREHENSION MOVEMENTS (1)
PRIMARY MOTOR CORTEX (1)
PSEUDO-NEGLECT (1)
REHABILITATION (1)
SELF (1)
SELF-AWARENESS (1)
more

Data set

Elsevier (39)
Wiley (4)
Springer (3)

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Search results for: Peter H. Weiss

Deficient allo‐centric visuospatial processing contributes to apraxic deficits in sub‐acute right hemisphere stroke

Anodal tDCS over left parietal cortex expedites recovery from stroke-induced apraxic imitation deficits: a pilot study

Action and semantic tool knowledge – Effective connectivity in the underlying neural networks

Using multi-level Bayesian lesion-symptom mapping to probe the body-part-specificity of gesture imitation skills

Timing independent spatial motor sequence learning is preserved in left hemisphere stroke

Error detection across the adult lifespan: Electrophysiological evidence for age-related deficits

Lesion evidence for a human mirror neuron system

Where language meets meaningful action: a combined behavior and lesion analysis of aphasia and apraxia

Deficits of reach-to-grasp coordination following stroke: Comparison of instructed and natural movements

Apraxia and spatial inattention dissociate in left hemisphere stroke

Subthalamic nucleus stimulation improves Parkinsonian gait via brainstem locomotor centers

Implicit interactions between number and space in digit-color synesthesia

Anosognosia, neglect, extinction and lesion site predict impairment of daily living after right-hemispheric stroke

Imagined tool-use in near and far space modulates the extra-striate body area

Functional synchronization in repetitive bimanual prehension movements

Visuo‐spatial representations of the alphabet in synaesthetes and non‐synaesthetes

The neural basis of perceptual bias and response bias in the Landmark task

Testing for neglect in right-hemispheric stroke patients using a new assessment battery based upon standardized activities of daily living (ADL)

Specific role of medial prefrontal cortex in retrieving recent autobiographical memories: An fMRI study of young female subjects

Altered neural network supporting declarative long-term memory in mild cognitive impairment

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